- New block polymer phases discovered by CEMS team featured in Science
- Research published in Biomicrofluidics could advance genome mapping technology
- Collaborative research on block polymer simulations featured in Macromolecules
- Researchers at UMN and BioNano Genomics improving genome mapping
- Muralidhar wins grand prize in MSI Research Exhibition
- Dorfman research highlighted in LC/GC newsletter
The research currently underway in the group centers around questions in polymer physics and microfluidic/nanofluidic technologies. On the polymer side, we are particularly interested in understanding the dynamics of DNA in confined systems, which allows us to simultaneously investigate the basic physical properties of semiflexible polymers while advancing genomics applications. In this area, we use a combination of experimental tools (fluorescence microscopy and nanofabrication), simulations (Brownian dynamics and Monte Carlo) and theory. There is a growing interest in the group on the thermodynamics of block polymers, largely in collaboration with Frank Bates, taking advantage of self-consistent field theory to study the formation of complex phases. On the microfluidics side, we have been working closely with Dan Frisbie on the development of new biosensors based on printed electronics and DNA aptamers. We are also using microchemostats developed in the group to study gene expression and the dynamics of bacterial DNA as part of a larger HFSP-funded collaboration.
- AES Electrophoresis Society Mid-Career Award, 2014
- Allan P. Colburn Award of the AIChE, 2012
- Guillermo E. Borja Award, 2012
- Camille Dreyfus Teacher-Scholar Award, 2010
- DARPA Young Faculty Award, 2009
- Packard Fellowship in Science and Engineering, 2007
- NSF CAREER Award, 2007
- Camille and Henry Dreyfus Foundation New Faculty Award, 2006
- Human Frontier Science Program Career Development Award, 2006
- Kyungtae Kim, Morgan W. Schulze, Akash Arora, Ronald M. Lewis III, Marc A. Hillmyer, Kevin D. Dorfman and Frank S. Bates. Thermal processing of diblock copolymer melts mimics metallurgy. Science 356, 520-523 (2017).
- Scott P. White, Srinand Sreevatsan, C. Daniel Frisbie and Kevin D. Dorfman, Rapid, selective, label-free aptameric capture and detection of ricin using a printed floating gate transistor. ACS Sensors 1, 1213-1216 (2016).
- Akash Arora, Jian Qin, David C. Morse, Kris T. Delaney, Glenn H. Fredrickson, Frank S. Bates, and Kevin D. Dorfman, Broadly accessible self-consistent field theory for block polymer materials discovery. Macromolecules 49, 4675-4690 (2016).
- Siddharth Chanpuriya, Kyugtae Kim, Jingwen Zhang, Sangwoo Lee, Akash Arora, Kevin D. Dorfman, Kris T. Delaney, Glenn H. Fredrickson and Frank S. Bates, Cornucopia of nanoscale ordered phases in sphere-forming tetrablock terpolymers. ACS Nano 10, 4961-4972 (2016).
- Damini Gupta, Jeremy J. Miller, Abhiram Muralidhar, Sara Mahshid, Walter Reisner and Kevin D. Dorfman, Experimental evidence of weak excluded volume effects for nanochannel confined DNA. ACS MacroLetters 4, 759-763 (2015).
- Douglas R. Tree, Yanwei Wang and Kevin D. Dorfman, Extension of DNA in a nanochannel as a rod-to-coil transition. Physical Review Letters 110, 208103 (2013).
- Liang Dai, Douglas R. Tree, Johan R. C. van der Maarel, Kevin D. Dorfman and Patrick S. Doyle, Revisiting blob theory for DNA diffusivity in slitlike confinement. Physical Review Letters 110, 168105 (2013).
- Kevin D. Dorfman, Scott B. King, Daniel W. Olson, Joel D. P. Thomas and Douglas R. Tree, Beyond gel electrophoresis: Microfluidic separations, fluorescence burst analysis, and DNA stretching. Chemical Reviews 113, 2584-2667 (2013).
- Douglas R. Tree, Yanwei Wang and Kevin D. Dorfman, Mobility of a semiflexible chain confined in a nanochannel. Physical Review Letters 108, 228105 (2012).
- Kevin D. Dorfman and Prodomos Daoutidis, Numerical Methods with Chemical Engineering Applications, Cambridge University Press (2017)